scholarly journals STERILE INSECT TECHNIQUE: A MODEL FOR DOSE OPTIMIZATION FOR IMPROVED STERILE INSECT QUALITY

2007 ◽  
Vol 90 (1) ◽  
pp. 88-95 ◽  
Author(s):  
Andrew Parker ◽  
Kishor Mehta
Keyword(s):  
Sterile Insect Technique ◽  
Dose Optimization ◽  
Insect Quality

Pharmacometrics in Dose Finding or Dose Optimization of Anti-Retroviral and Anti-Tubercular Drugs

2011 ◽  
Vol 11 (2) ◽  
pp. 157-166
Author(s):  
Sreedharan Nair Sabarinath ◽  
Benjamin Wu ◽  
Charles Peloquin ◽  
Hartmut Derendorf
Keyword(s):  
Dose Finding ◽  
Dose Optimization

USE OF CLINICAL EXPOSURE INDEX AND DEVIATION INDEX BASED ON NATIONAL DIAGNOSTIC REFERENCE LEVEL AS DOSE-OPTIMIZATION TOOLS FOR GENERAL RADIOGRAPHY IN KOREA

2020 ◽  
Vol 191 (4) ◽  
pp. 439-451
Author(s):  
Hyemin Park ◽  
Yongsu Yoon ◽  
Jungmin Kim ◽  
Jungsu Kim ◽  
Hoiwoun Jeong ◽  
...  
Keyword(s):  
Patient Dose ◽  
Reference Level ◽  
Dose Optimization ◽  
International Electrotechnical Commission ◽  
Exposure Index ◽  
Clinical Exposure ◽  
Deviation Index ◽  
Clinical Environments ◽  
Anterior Posterior ◽  
Exposure Conditions

Abstract The International Electrotechnical Commission introduced the concepts of exposure index (EI), target exposure index (EIT) and deviation index (DI) to manage and optimize patient dose in real time. In this study, we have proposed an appropriate method for setting the EIT based on the Korean national diagnostic reference levels (DRLs). Furthermore, we evaluated the use of clinical EI, EIT and DI as tools for patient dose optimization in clinical environments by observing the changes in DI with those in EIT. According to the Korean national exposure conditions, we conducted experiments on three representative radiographic examinations (chest posterior–anterior, lateral and abdomen anterior–posterior) of clinical environments. As the exposure conditions and DRLs varied, the clinical EI, EIT and DI also varied. These results reveal that the clinical EI, EIT and DI can be used as tools for optimizing the patient dose if EIT is periodically and properly updated.

Remating in Ceratitis capitata sterile males: Implications in sterile insect technique programmes

2021 ◽  
Author(s):  
Marta Catalá‐Oltra ◽  
Elena Llácer ◽  
Oscar Dembilio ◽  
Ignacio Pla ◽  
Alberto Urbaneja ◽  
...  
Keyword(s):  
Sterile Insect Technique ◽  
Ceratitis Capitata

scholarly journals Genetic analysis of medfly populations in an area of sterile insect technique applications

2021 ◽  
Author(s):  
Rubén Sancho ◽  
Ana Guillem-Amat ◽  
Elena López-Errasquín ◽  
Lucas Sánchez ◽  
Félix Ortego ◽  
...  
Keyword(s):  
Genetic Markers ◽  
Sterile Insect Technique ◽  
Ceratitis Capitata ◽  
Natural Populations ◽  
Low Frequency ◽  
Fruit Fly ◽  
Wild Populations ◽  
Genetic Sexing ◽  
Environmental Implications ◽  
Genetic Sexing Strains

AbstractThe sterile insect technique (SIT) is widely used in integrated pest management programs for the control of the Mediterranean fruit fly (medfly), Ceratitis capitata. The genetic interactions between the released individuals from the genetic sexing strains (GSS), used for SIT applications worldwide, and wild individuals have not been studied. Under the hypothesis that a number of Vienna GSS individuals released to the field might not be completely sterile and may produce viable offspring, we have analyzed medfly Spanish field populations to evaluate the presence of Vienna strain genetic markers. To this goal, we have used contrasted nuclear and mitochondrial genetic markers, and two novel sets of nuclear polymorphisms with the potential to be markers to discriminate between Vienna and wild individuals. Nuclear Vienna markers located on the 5th chromosome of Vienna males have been found in 2.2% (19 from 875) of the Spanish wild medfly females captured at the area where SIT is applied. In addition, a female-inherited mitochondrial Vienna marker has been found in two from the 19 females showing nuclear Vienna markers. The detection of several of these markers in single individuals represents evidence of the introgression of Vienna strain into natural populations. However, alternative explanations as their presence at low frequency in wild populations in the studied areas cannot be fully discarded. The undesired release of non-fully sterile irradiated GSS individuals into the field and their interactions with wild flies, and the potential environmental implications should be taken into account in the application of the SIT.

Implementation of dose point kernel (DPK) for dose optimization of 177Lu/90Y cocktail radionuclides in internal dosimetry

2021 ◽  
Vol 173 ◽  
pp. 109673
Author(s):  
Milad Peer-Firozjaei ◽  
Mohammad Ali Tajik-Mansoury ◽  
Parham Geramifar ◽  
Ali Asghar Parach ◽  
Shiva Zarifi
Keyword(s):  
Dose Optimization ◽  
Internal Dosimetry
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